Huacong Chen

Notable Works

• Xu H, Li J, Chen H, Wang C, Ghishan FK. “NHE8 plays important roles in gastric mucosal protection.” Am J Physiol Gastrointest Liver Physiol. 304: G257-61, 2013. 
• Xu H, Zhang B, Li J, Wang C, Chen H, Ghishan FK. Impaired mucin synthesis and bicarbonate secretion in the colon of NHE8 Knockout mice. Am J Physiol Gastrointest Liver Physiol. 303: G335-43, 2012. 
• Xu H, Li J, Chen R, Zhang B, Wang C, King N, Chen H, Ghishan FK. NHE2X3 DKO mice exhibit gender-specific NHE8 compensation. Am J Physiol Gastrointest Liver Physiol. 300(4):G647-53, 2011. 
• Wang C, Xu H, Chen H, Li J, Zhang B, Tang C, Ghishan FK. Somatostatin stimulates intestinal NHE8 expression via p38 MAPK pathway. Am J Physiol Cell Physiol. 300(2):C375-82, 2011. 
• Xu H, Zhang B, Li J, Chen H, Tooley J, Ghishan FK. Epidermal growth factor inhibits intestinal NHE8 expression via reducing its basal transcription. Am J Physiol Cell Physiol. 299:C51-7, 2010. 
• Xu H, Zhang B, Li J, Chen H, Wang C, Ghishan FK. Transcriptional inhibition of intestinal NHE8 expression by glucocorticoids involves Pax5. Am J Physiol Gastrointest Liver Physiol. 299:G921-7, 2010. 
• Chen H, Xu H, Dong J, Li J, Ghishan FK. Tumor necrosis factor-alpha impairs intestinal phosphate absorption in colitis. Am J Physiol Gastrointest Liver Physiol. 296:G775-781, 2009. 
• Xu H, Chen H, Dong J, Li J, Chen R, Uno JK, Ghishan FK.  Tumor Necrosis Factor Alpha Down-Regulates Intestinal NHE8 Expression by Reducing Basal Promoter Activity. Am J Physiol Cell Physiol. 296:C489-97, 2008. 
• Xu H, Chen H, Dong J, Lynch R, Ghishan FK. Gastrointestinal Distribution and Kinetic Characterization of the Sodium-Hydrogen Exchanger Isoform 8 (NHE8). Cell Physiol Biochem.21:109-116; 2008.